Article
Rare co-existence of mutation in KRAS and ALK gene re-arrangement in an adenocarcinoma patient--a case report.
Anticancer research - 1 Jul 2014
Homa Iwona, Sawicki Marek, Wojas-Krawczyk Kamila, Nicoś Marcin, Mlak Radosław, Powrózek Tomasz, Krawczyk Paweł, Przybylski Piotr, Czekajska-Chehab Elżbieta, Milanowski Janusz
Abstract excerpt
Anaplastic lymphoma kinase (ALK) gene re-arrangements are present in approximately 4% of patients with non-small cell lung cancer (NSCLC), mostly in non-smokers with adenocarcinoma. V-KI-RAS2 Kirsten rat sarcoma viral oncogene homolog (KRAS) mutations are more common in smokers. These molecular l...
Topics
- Adenocarcinoma
- Adenocarcinoma of Lung
- Anaplastic Lymphoma Kinase
- Gene Rearrangement
- Genes, ras
- Humans
- Lung Neoplasms
- Male
- Middle Aged
- Mutation
- Proto-Oncogene Proteins
- Proto-Oncogene Proteins p21(ras)
- Receptor Protein-Tyrosine Kinases
- Smoking
- ras Proteins