Article
Antibody blocks acquisition of bacterial colonization through agglutination.
Mucosal immunology - 1 Jan 2015
Roche A M, Richard A L, Rahkola J T, Janoff E N, Weiser J N
Abstract excerpt
Invasive infection often begins with asymptomatic colonization of mucosal surfaces. A murine model of bacterial colonization with Streptococcus pneumoniae was used to study the mechanism for mucosal protection by immunoglobulin. In previously colonized immune mice, bacteria were rapidly sequestered within large aggregates in the nasal lumen. To further examine the role of bacterial agglutination in protection by...
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