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Article

An Axis Involving SNAI1, microRNA-128 and SP1 Modulates Glioma Progression

24 Jun 2014

Abstract excerpt

BACKGROUND: Glioblastoma is an extraordinarily aggressive disease that requires more effective therapeutic options. Snail family zinc finger 1, dysregulated in many neoplasms, has been reported to be involved in gliomas. However, the biological mechanisms underlying SNAI1 function in gliomas need further investigation. METHODS: Quantitative real-time PCR was used to measure microRNA-128 (miR-128) expression level...

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PMID: 24959930
DOI: 10.1371/journal.pone.0098651

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