Article
Modeling the phenotypic architecture of autism symptoms from time of diagnosis to age 6.
Journal of autism and developmental disorders - 1 Dec 2014
Georgiades Stelios, Boyle Michael, Szatmari Peter, Hanna Steven, Duku Eric, Zwaigenbaum Lonnie, Bryson Susan, Fombonne Eric, Volden Joanne, Mirenda Pat, Smith Isabel, Roberts Wendy, Vaillancourt Tracy, Waddell Charlotte, Bennett Teresa, Elsabbagh Mayada, Thompson Ann
Abstract excerpt
The latent class structure of autism symptoms from the time of diagnosis to age 6 years was examined in a sample of 280 children with autism spectrum disorder. Factor mixture modeling was performed on 26 algorithm items from the Autism Diagnostic Interview - Revised at diagnosis (Time 1) and again at age 6 (Time 2). At Time 1, a "2-factor/3-class" model provided the best fit to the data. At Time 2, a...
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