Article
Potentially pathogenic airway bacteria and neutrophilic inflammation in treatment resistant severe asthma.
PloS one - 1 Jan 2014
Green Benjamin J, Wiriyachaiporn Surasa, Grainge Christopher, Rogers Geraint B, Kehagia Valia, Lau Laurie, Carroll Mary P, Bruce Kenneth D, Howarth Peter H
Abstract excerpt
BACKGROUND: Molecular microbiological analysis of airway samples in asthma has demonstrated an altered microbiome in comparison to healthy controls. Such changes may have relevance to treatment-resistant severe asthma, particularly those with neutrophilic airway inflammation, as bacteria might be anticipated to activate the innate immune response, a process that is poorly steroid responsive. An understanding of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.