Article
Insights into pathophysiology of dystropy through the analysis of gene networks: an example of bronchial asthma and tuberculosis.
Immunogenetics - 1 Aug 2014
Bragina Elena Yu, Tiys Evgeny S, Freidin Maxim B, Koneva Lada A, Demenkov Pavel S, Ivanisenko Vladimir A, Kolchanov Nikolay A, Puzyrev Valery P
Abstract excerpt
Co-existence of bronchial asthma (BA) and tuberculosis (TB) is extremely uncommon (dystropic). We assume that this is caused by the interplay between genes involved into specific pathophysiological pathways that arrest simultaneous manifestation of BA and TB. Identification of common and specific genes may be important to determine the molecular genetic mechanisms leading to rare co-occurrence of these diseases...
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