Article
Differential reparative phenotypes between zebrafish and medaka after cardiac injury.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Sept 2014
Ito Kohei, Morioka Mai, Kimura Shun, Tasaki Mai, Inohaya Keiji, Kudo Akira
Abstract excerpt
BACKGROUND: Zebrafish have the ability for heart regeneration. However, another teleost animal model, the medaka, had not yet been investigated for this capacity. RESULTS: Compared with zebrafish, the medaka heart responded differently to an injury: An excessive fibrotic response occurred in the medaka heart, and existing cardiomyocytes or cardiac progenitor cells remained dormant, resulting in no numerical...
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