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Article

Clinical and molecular features of 38 children with chronic granulomatous disease in mainland china.

Journal of clinical immunology - 1 Aug 2014

Xu Huan, Tian Wen, Li Shu-Juan, Zhang Lu-Ying, Liu Wei, Zhao Yao, Zhang Zhi-Yong, Tang Xue-Mei, Wang Mo, Wu Dao-Qi, Shi Ji-Sheng, Ding Yuan, Zhao Xiao-Dong, Yang Xi-Qiang, Jiang Li-Ping

Abstract excerpt

PURPOSE: Chronic granulomatous disease (CGD) is an inherited disorder, with phagocytes failing to produce antimicrobial superoxide due to deficient NADPH oxidase activity. Mutations in the gene encoding CYBB are responsible for the majority of the CGD cases. To date, there have been no reports on large samples of children with CGD in China. Therefore, in this study, we described the clinical and molecular...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24943880
DOI: 10.1007/s10875-014-0061-0

Genes

CYBB
CYBA
NCF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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