Article
Mycoplasma pneumoniae thymidine phosphorylase.
Nucleosides, nucleotides & nucleic acids - 1 Jan 2014
Wang Liya, Schmidl Sebastian R, Stülke Jörg
Abstract excerpt
Mycoplasma pneumoniae (Mpn) is a human pathogen causing acute respiratory diseases and accounts for approximately 30% cases of community-acquired pneumonia. Co-infection with Mycoplasmas compromises the efficacy of anticancer and antiviral nucleoside analog-based drugs due to the presence of Mycoplasma thymidine phosphorylase (TP). In this study, a TP-deficient strain of Mpn was generated in order to study the...
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