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Article

Inhibition of exotoxin production by mobile genetic element SCCmec-encoded psm-mec RNA is conserved in staphylococcal species.

PloS one - 1 Jan 2014

Ikuo Mariko, Nagano Gentaro, Saito Yuki, Mao Han, Sekimizu Kazuhisa, Kaito Chikara

Abstract excerpt

Staphylococcal species acquire antibiotic resistance by incorporating the mobile-genetic element SCCmec. We previously found that SCCmec-encoded psm-mec RNA suppresses exotoxin production as a regulatory RNA, and the psm-mec translation product increases biofilm formation in Staphylococcus aureus. Here, we examined whether the regulatory role of psm-mec on host bacterial virulence properties is conserved among...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24926994
DOI: 10.1371/journal.pone.0100260
PMCID: PMC4057442

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