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Article

Small-colony variants and phenotype switching of intracellular Staphylococcus aureus in chronic rhinosinusitis.

Allergy - 1 Oct 2014

Tan N C-W, Cooksley C M, Roscioli E, Drilling A J, Douglas R, Wormald P-J, Vreugde S

Abstract excerpt

BACKGROUND: Chronic rhinosinusitis (CRS) has been linked to the gram-positive bacteria Staphylococcus aureus (S. aureus) in its biofilm or intracellular forms. Recent evidence suggests that S. aureus also exists in a small-colony variant (SCV) form as a mechanism of altering its virulence capabilities. The aim of this study was to investigate the presence of SCVs in sinonasal mucosa of CRS patients and whether...

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PMID: 24922342
DOI: 10.1111/all.12457

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