Article
Sofosbuvir (Sovaldi) for the treatment of hepatitis C.
Expert review of clinical pharmacology - 1 Sept 2014
Lam Brian, Henry Linda, Younossi Zobair
Abstract excerpt
Hepatitis C (HCV) remains an important cause of chronic liver disease worldwide. Historically, treatment included pegylated-interferon and ribavirin with low efficacy and numerous side effects contributing to poor adherence and impairment of patients' well-being. The next step in developing better treatment regimens for HCV led to the development of the first-generation direct acting antivirals (DAAs). Although...
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