Article
Mechanisms of reduced susceptibility and genotypic prediction of antibiotic resistance in Prevotella isolated from cystic fibrosis (CF) and non-CF patients.
The Journal of antimicrobial chemotherapy - 1 Oct 2014
Sherrard Laura J, Schaible Bettina, Graham Kathryn A, McGrath Stef J, McIlreavey Leanne, Hatch Joseph, Wolfgang Matthew C, Muhlebach Marianne S, Gilpin Deirdre F, Schneiders Thamarai, Elborn J Stuart, Tunney Michael M
Abstract excerpt
OBJECTIVES: To investigate mechanisms of reduced susceptibility to commonly used antibiotics in Prevotella cultured from patients with cystic fibrosis (CF), patients with invasive infection and healthy control subjects and to determine whether genotype can be used to predict phenotypic resistance. METHODS: The susceptibility of 157 Prevotella isolates to seven antibiotics was compared, with detection of...
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