Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Kaposi's sarcoma-associated herpesvirus ORF6 gene is essential in viral lytic replication.

PloS one - 1 Jan 2014

Peng Can, Chen Jungang, Tang Wei, Liu Chunlan, Chen Xulin

Abstract excerpt

Kaposi's sarcoma associated herpesvirus (KSHV) is associated with Kaposis's sarcoma (KS), primary effusion lymphoma and multicentric Castleman's disease. KSHV encodes at least 8 open reading frames (ORFs) that play important roles in its lytic DNA replication. Among which, ORF6 of KSHV encodes an ssDNA binding protein that has been proved to participate in origin-dependent DNA replication in transient assays. To...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Gene Deletion
Share to Genetic Complementation Test
Share to Genome, Viral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Herpesviridae Infections

Share to Herpesvirus 8, Human

Share to Open Reading Frames

Share to Viral Proteins

Share to Virus Replication

Source

Open in PubMed Open full text

Identifiers

PMID: 24911362
DOI: 10.1371/journal.pone.0099542
PMCID: PMC4050029

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Kaposi's sarcoma-associated herpesvirus ORF6 gene is essential in viral lytic replication.PMID 24911362Read ↗

The Kaposi's-sarcoma-associated herpesvirus orf35 gene product is required for efficient lytic virus reactivation.Semantic proximity Read ↗

Efficient infection by a recombinant Kaposi's sarcoma-associated herpesvirus cloned in a bacterial artificial chromosome: application for genetic analysis.Semantic proximity Read ↗

Construction of a Lytically Replicating Kaposi's Sarcoma-Associated HerpesvirusSemantic proximity Read ↗

Kaposi’s sarcoma-associated herpesvirus ORF67.5 functions as a component of the terminase complexSemantic proximity Read ↗

Kaposi's Sarcoma-Associated Herpesvirus ORF18 and ORF30 Are Essential for Late Gene Expression during Lytic ReplicationSemantic proximity Read ↗

Kaposi's Sarcoma-Associated Herpesvirus Bacterial Artificial Chromosome Contains a Duplication of a Long Unique-Region Fragment within the Terminal Repeat RegionSemantic proximity Read ↗

Kaposi’s sarcoma-associated herpesvirus ORF34 is essential for late gene expression and virus productionSemantic proximity Read ↗

Productive Lytic Replication of a Recombinant Kaposi's Sarcoma-Associated Herpesvirus in Efficient Primary Infection of Primary Human Endothelial CellsSemantic proximity Read ↗

A Kaposi's Sarcoma-Associated Herpesvirus/Human Herpesvirus 8 ORF50 Deletion Mutant Is Defective for Reactivation of Latent Virus and DNA ReplicationSemantic proximity Read ↗

Identification of the Physiological Gene Targets of the Essential Lytic Replicative Kaposi's Sarcoma-Associated Herpesvirus ORF57 ProteinSemantic proximity Read ↗

Kaposi's Sarcoma-Associated Herpesvirus Lytic Gene ORF57 Is Essential for Infectious Virion ProductionSemantic proximity Read ↗

Kaposi’s Sarcoma-Associated Herpesvirus ORF67.5 Functions as a Component of the Terminase ComplexSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.