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MFS multidrug transporters in pathogenic fungi: do they have real clinical impact?

28 May 2014

Abstract excerpt

Infections caused by opportunistic fungal pathogens have reached concerning numbers due to the increase of the immunocrompromised human population and to the development of antifungal resistance. This resistance is often attributed to the action of multidrug efflux pumps, belonging to the ATP-binding cassette (ABC) superfamily and the major facilitator superfamily (MFS). Although many studies have focused on the...

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PMID: 24904431
DOI: 10.3389/fphys.2014.00197

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