Article
A comparison of two informative SNP-based strategies for typing Pseudomonas aeruginosa isolates from patients with cystic fibrosis.
BMC infectious diseases - 5 Jun 2014
Syrmis Melanie W, Kidd Timothy J, Moser Ralf J, Ramsay Kay A, Gibson Kristen M, Anuj Snehal, Bell Scott C, Wainwright Claire E, Grimwood Keith, Nissen Michael, Sloots Theo P, Whiley David M
Abstract excerpt
BACKGROUND: Molecular typing is integral for identifying Pseudomonas aeruginosa strains that may be shared between patients with cystic fibrosis (CF). We conducted a side-by-side comparison of two P. aeruginosa genotyping methods utilising informative-single nucleotide polymorphism (SNP) methods; one targeting 10 P. aeruginosa SNPs and using real-time polymerase chain reaction technology (HRM10SNP) and the other...
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