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Article

Effect of female genital schistosomiasis and anti-schistosomal treatment on monocytes, CD4+ T-cells and CCR5 expression in the female genital tract.

PloS one - 1 Jan 2014

Kleppa Elisabeth, Ramsuran Veron, Zulu Siphosenkosi, Karlsen Gunn Hege, Bere Alfred, Passmore Jo-Ann S, Ndhlovu Patricia, Lillebø Kristine, Holmen Sigve D, Onsrud Mathias, Gundersen Svein Gunnar, Taylor Myra, Kjetland Eyrun F, Ndung'u Thumbi

Abstract excerpt

BACKGROUND: Schistosoma haematobium is a waterborne parasite that may cause female genital schistosomiasis (FGS), characterized by genital mucosal lesions. There is clinical and epidemiological evidence for a relationship between FGS and HIV. We investigated the impact of FGS on HIV target cell density and expression of the HIV co-receptor CCR5 in blood and cervical cytobrush samples. Furthermore we evaluated the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24896815
DOI: 10.1371/journal.pone.0098593
PMCID: PMC4045760

Genes

CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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