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Article

SMaSH: a benchmarking toolkit for human genome variant calling.

Bioinformatics (Oxford, England) - 1 Oct 2014

Talwalkar Ameet, Liptrap Jesse, Newcomb Julie, Hartl Christopher, Terhorst Jonathan, Curtis Kristal, Bresler Ma'ayan, Song Yun S, Jordan Michael I, Patterson David

Abstract excerpt

MOTIVATION: Computational methods are essential to extract actionable information from raw sequencing data, and to thus fulfill the promise of next-generation sequencing technology. Unfortunately, computational tools developed to call variants from human sequencing data disagree on many of their predictions, and current methods to evaluate accuracy and computational performance are ad hoc and incomplete....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24894505
DOI: 10.1093/bioinformatics/btu345
PMCID: PMC4173010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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