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Article

Rab18 and a Rab18 GEF complex are required for normal ER structure.

The Journal of cell biology - 9 Jun 2014

Gerondopoulos Andreas, Bastos Ricardo Nunes, Yoshimura Shin-Ichiro, Anderson Rachel, Carpanini Sarah, Aligianis Irene, Handley Mark T, Barr Francis A

Abstract excerpt

The ancestral Rab GTPase Rab18 and both subunits of the Rab3GAP complex are mutated in the human neurological and developmental disorder Warburg Micro syndrome. Here, we demonstrate that the Rab3GAP complex is a specific Rab18 guanine nucleotide exchange factor (GEF). The Rab3GAP complex localize...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24891604
DOI: 10.1083/jcb.201403026
PMCID: PMC4050724

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24891604-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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