Article
Virologic characterization of genotype 4 hepatitis C virus variants in patients treated with telaprevir.
Virology journal - 16 May 2014
De Meyer Sandra, Ghys Anne, Dierynck Inge, Beumont Maria, Luo Donghan, Picchio Gaston
Abstract excerpt
BACKGROUND: Study C210 was a Phase IIa, exploratory trial to assess the activity of telaprevir on hepatitis C virus (HCV) early viral kinetics in treatment-naïve patients infected with genotype 4 (G4) HCV. METHODS: Patients were randomized to receive peginterferon and ribavirin alone, telaprevir monotherapy (T arm), or telaprevir in combination with peginterferon/ribavirin (TPR arm) for 15 days, followed by a 46-...
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