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Article

Telaprevir with peginterferon and ribavirin for chronic HCV genotype 1 infection.

The New England journal of medicine - 30 Apr 2009

McHutchison John G, Everson Gregory T, Gordon Stuart C, Jacobson Ira M, Sulkowski Mark, Kauffman Robert, McNair Lindsay, Alam John, Muir Andrew J

Abstract excerpt

BACKGROUND: Current therapy for chronic hepatitis C virus (HCV) infection is effective in less than 50% of patients infected with HCV genotype 1. Telaprevir, a protease inhibitor specific to the HCV nonstructural 3/4A serine protease, rapidly reduced HCV RNA levels in early studies. METHODS: We r...

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PMID: 19403902
DOI: 10.1056/NEJMoa0806104

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19403902-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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