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Article

Epidermal growth factor receptor mutations and anaplastic lymphoma kinase rearrangements in lung cancer with nodular ground-glass opacity.

BMC cancer - 3 May 2014

Ko Sung-Jun, Lee Yeon Joo, Park Jong Sun, Cho Young-Jae, Yoon Ho Il, Chung Jin-Haeng, Kim Tae Jung, Lee Kyung Won, Kim Kwhanmien, Jheon Sanghoon, Kim Hyojin, Lee Jae Ho, Lee Choon-Taek

Abstract excerpt

BACKGROUND: Nodular ground-glass opacities (nGGO) are a specific type of lung adenocarcinoma. ALK rearrangements and driver mutations such as EGFR and K-ras are frequently found in all types of lung adenocarcinoma. EGFR mutations play a role in the early carcinogenesis of nGGOs, but the role of ALK rearrangement remains unknown. METHODS: We studied 217 nGGOs resected from 215 lung cancer patients. Pathology,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24885886
DOI: 10.1186/1471-2407-14-312
PMCID: PMC4022408

Genes

ALK
EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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