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Article

Gestational stage affects amniotic epithelial cells phenotype, methylation status, immunomodulatory and stemness properties.

Stem cell reviews and reports - 1 Oct 2014

Barboni Barbara, Russo Valentina, Curini Valentina, Martelli Alessandra, Berardinelli Paolo, Mauro Annunziata, Mattioli Mauro, Marchisio Marco, Bonassi Signoroni Patrizia, Parolini Ornella, Colosimo Alessia

Abstract excerpt

Stem cells isolated from amniotic epithelium (AECs) have shown great potential in cell-based regenerative therapies. Because of their fetal origin, these cells exhibit elevated proliferation rates and plasticity, as well as, immune tolerance and anti-inflammatory properties. These inherent attitudes make AECs well-suited for both allogenic and xenogenic cellular transplants in animal models. Since in human only...

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Identifiers

PMID: 24867872
DOI: 10.1007/s12015-014-9519-y
PMCID: PMC4167432

Genes

NANOG
SOX2
TERT
LPL
NEFM

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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