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Article

Embryo number and periconceptional undernutrition in the sheep have differential effects on adrenal epigenotype, growth, and development.

American journal of physiology. Endocrinology and metabolism - 15 Jul 2014

Williams-Wyss Olivia, Zhang Song, MacLaughlin Severence M, Kleemann David, Walker Simon K, Suter Catherine M, Cropley Jennifer E, Morrison Janna L, Roberts Claire T, McMillen I Caroline

Abstract excerpt

Exposure to poor maternal nutrition around the time of conception results in an early prepartum activation of the fetal pituitary-adrenal axis and in increased adrenal growth and stress response after birth associated with epigenetic changes in a differentially methylated region (DMR) of adrenal...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24844259
DOI: 10.1152/ajpendo.00051.2012
PMCID: PMC4101636

Genes

IGF2
CRH
IGF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24844259-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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