Disorders of aldosterone synthesis, secretion, and cellular function.

doi:10.1097/MOP.0000000000000104

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Article

Disorders of aldosterone synthesis, secretion, and cellular function.

Current opinion in pediatrics - 1 Aug 2014

Root Allen W

Abstract excerpt

PURPOSE OF REVIEW: The purpose of this review is to describe the renin-angiotensin-aldosterone system and its regulatory control of sodium, potassium, chloride, hydrogen ion, and water homeostasis through its effects on the expression and activity of distal renal tubular cotransporter proteins and to discuss the gene mutations encoding these structures that disturb the function of this system. RECENT FINDINGS:...

Topics

Aldosterone
Humans
Hypoaldosteronism
Mutation
Potassium
Receptors, Mineralocorticoid
Renin-Angiotensin System
Sodium

Source

Open in PubMed

Identifiers

PMID: 24840884
DOI: 10.1097/MOP.0000000000000104

Genes

WNK4
CUL3
WNK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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