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Increased oxidative stress and impaired antioxidant response in Lafora disease.

Molecular neurobiology - 1 Jan 2015

Romá-Mateo Carlos, Aguado Carmen, García-Giménez José Luis, Ibáñez-Cabellos José Santiago, Seco-Cervera Marta, Pallardó Federico V, Knecht Erwin, Sanz Pascual

Abstract excerpt

Lafora disease (LD, OMIM 254780, ORPHA501) is a fatal neurodegenerative disorder characterized by the presence of glycogen-like intracellular inclusions called Lafora bodies and caused, in the vast majority of cases, by mutations in either EPM2A or EPM2B genes, encoding respectively laforin and malin. In the last years, several reports have revealed molecular details of these two proteins and have identified...

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PMID: 24838580
DOI: 10.1007/s12035-014-8747-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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