Article
Lung transplantation in telomerase mutation carriers with pulmonary fibrosis.
The European respiratory journal - 1 Jul 2014
Silhan Leann L, Shah Pali D, Chambers Daniel C, Snyder Laurie D, Riise Gerdt C, Wagner Christa L, Hellström-Lindberg Eva, Orens Jonathan B, Mewton Juliette F, Danoff Sonye K, Arcasoy Murat O, Armanios Mary
Abstract excerpt
Lung transplantation is the only intervention that prolongs survival in idiopathic pulmonary fibrosis (IPF). Telomerase mutations are the most common identifiable genetic cause of IPF, and at times, the telomere defect manifests in extrapulmonary disease such as bone marrow failure. The relevance of this genetic diagnosis for lung transplant management has not been examined. We gathered an international series of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.