Article
Trophoblast retrieval and isolation from the cervix (TRIC) for noninvasive prenatal screening at 5 to 20 weeks of gestation.
Fertility and sterility - 1 Jul 2014
Bolnick Jay M, Kilburn Brian A, Bajpayee Swati, Reddy Nitya, Jeelani Roohi, Crone Barbara, Simmerman Neil, Singh Manivinder, Diamond Michael P, Armant D Randall
Abstract excerpt
OBJECTIVE: To use trophoblast cells accumulating in the endocervical canal at the beginning of pregnancy for noninvasive prenatal testing. DESIGN: Prospective, double-blinded test for fetal gender. SETTING: Academic medical center. PATIENT(S): Fifty-six women with singleton pregnancies at gestational age 5-20 weeks. INTERVENTION(S): Isolation of fetal cells from resident maternal cells in endocervical specimens...
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