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Article

Evidence for feasibility of fetal trophoblastic cell‐based noninvasive prenatal testing

12 Sept 2016

Abstract excerpt

OBJECTIVE: The goal was to develop methods for detection of chromosomal and subchromosomal abnormalities in fetal cells in the mother's circulation at 10-16 weeks' gestation using analysis by array comparative genomic hybridization (CGH) and/or next-generation sequencing (NGS). METHOD: Nucleated cells from 30 mL of blood collected at 10-16 weeks' gestation were separated from red cells by density fractionation...

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Share to Genomic variations and chromosomal abnormalities
Share to Gestational Trophoblastic Disease Studies
Share to Prenatal Screening and Diagnostics

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PMID: 27616633
DOI: 10.1002/pd.4924

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