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Article

Inherited thrombotic thrombocytopenic purpura in children.

Seminars in thrombosis and hemostasis - 1 Jun 2014

Hassenpflug Wolf Achim, Budde Ulrich, Schneppenheim Sonja, Schneppenheim Reinhard

Abstract excerpt

Congenital thrombotic thrombocytopenic purpura (TTP) or Upshaw-Schulman syndrome is caused by homozygous or compound heterozygous mutations in the ADAMTS-13 (a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13) gene. We investigated 30 patients with congenital TTP and analyzed clinical data and underlying ADAMTS-13 mutations. All patients showed virtually no ADAMTS-13 activity in...

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Source

Identifiers

PMID: 24816970
DOI: 10.1055/s-0034-1376152

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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