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Article

BRAFV600E-mutant melanoma presenting with cardiac involvement.

Journal of the National Comprehensive Cancer Network : JNCCN - 1 May 2014

Johnson Douglas B, Sosman Jeffrey A

Abstract excerpt

Melanoma is an aggressive skin cancer with historically limited treatment options. Approximately 50% of melanomas harbor BRAF(V600) mutations. This report describes a 32-year-old man with metastatic BRAF(V600)-mutant melanoma who presented with cardiac involvement. Recently developed treatment options for patients with BRAF-mutant melanoma include BRAF inhibitors (vemurafenib, dabrafenib), MEK inhibitors...

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Share to BRAF gene
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Proto-Oncogene Proteins B-raf

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Source

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Identifiers

PMID: 24812130
DOI: 10.6004/jnccn.2014.0065
PMCID: PMC4182311

Genes

BRAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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