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Article

Is it possible to change phenotype progression in Crohn's disease in the era of immunomodulators? Predictive factors of phenotype progression.

The American journal of gastroenterology - 1 Jul 2014

Magro Fernando, Rodrigues-Pinto Eduardo, Coelho Rosa, Andrade Patrícia, Santos-Antunes João, Lopes Susana, Camila-Dias Claudia, Macedo Guilherme

Abstract excerpt

OBJECTIVES: Crohn's disease (CD) induces cumulative structural damage, initially characterized by a non-stenosing non-penetrating behavior (B1) with progression over time to a fibro-stenosing (B2) and/or penetrating phenotype (B3). Our aim was to assess the long-term evolution of disease behavior of CD and determine what factors predict phenotype progression. METHODS: This was a study based on prospectively...

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PMID: 24796767
DOI: 10.1038/ajg.2014.97

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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