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Article

A rolling phenotype in Crohn's disease.

PloS one - 1 Jan 2017

Irwin James, Ferguson Emma, Simms Lisa A, Hanigan Katherine, Carbonnel Franck, Radford-Smith Graham

Abstract excerpt

BACKGROUND AND AIM: The Montreal classification of disease behaviour in Crohn's disease describes progression of disease towards a stricturing and penetrating phenotype. In the present paper, we propose an alternative representation of the long-term course of Crohn's disease complications, the rolling phenotype. As is commonly observed in clinical practice, this definition allows progression to a more severe...

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Adolescent
Crohn Disease
Longitudinal Studies
Phenotype
Young Adult

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PMID: 28384331
DOI: 10.1371/journal.pone.0174954
PMCID: PMC5383106

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