Article
Genome-wide association study identifies ALLC polymorphisms correlated with FEV₁ change by corticosteroid.
Clinica chimica acta; international journal of clinical chemistry - 25 Sept 2014
Park Tae-Joon, Park Jong-Sook, Cheong Hyun Sub, Park Byung-Lae, Kim Lyoung Hyo, Heo Jeong Seok, Kim Yang Ki, Kim Ki-Up, Uh Soo-Taek, Lee Ho Sung, Na Joo-Ock, Seo Ki-Hyun, Choi Jae-Sung, Kim Yong Hoon, Kim Myung-Sin, Park Choon-Sik, Shin Hyoung Doo
Abstract excerpt
OBJECTIVES: Asthma can be suppressed by inhaled corticosteroids (ICS). However, response to ICS shows marked inter-individual variability. This study is aimed to identify the genetic variants associated with the change in the percentage of forced expiratory volume in 1second (%ΔFEV1) following ICS treatment. METHODS: A genome-wide association study was performed in a Korean asthmatic cohort. To further...
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