Article
Synergistic effects of Clostridium perfringens enterotoxin and beta toxin in rabbit small intestinal loops.
Infection and immunity - 1 Jul 2014
Ma Menglin, Gurjar Abhijit, Theoret James R, Garcia Jorge P, Beingesser Juliann, Freedman John C, Fisher Derek J, McClane Bruce A, Uzal Francisco A
Abstract excerpt
The ability of Clostridium perfringens type C to cause human enteritis necroticans (EN) is attributed to beta toxin (CPB). However, many EN strains also express C. perfringens enterotoxin (CPE), suggesting that CPE could be another contributor to EN. Supporting this possibility, lysate supernatants from modified Duncan-Strong sporulation (MDS) medium cultures of three CPE-positive type C EN strains caused...
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