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Article

UV signaling pathways within the skin.

The Journal of investigative dermatology - 1 Aug 2014

Chen Hongxiang, Weng Qing Y, Fisher David E

Abstract excerpt

The effects of UVR on the skin include tanning, carcinogenesis, immunomodulation, and synthesis of vitamin D, among others. Melanocortin 1 receptor polymorphisms correlate with skin pigmentation, UV sensitivity, and skin cancer risk. This article reviews pathways through which UVR induces cutaneous stress and the pigmentation response. Modulators of the UV-tanning pathway include sunscreen agents, melanocortin 1...

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Share to Ultraviolet Rays
Share to Adenylyl Cyclases
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Microphthalmia-Associated Transcription Factor

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Share to Receptor, Melanocortin, Type 1

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Source

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Identifiers

PMID: 24759085
DOI: 10.1038/jid.2014.161
PMCID: PMC4102648

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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