Superantigen profiling of Staphylococcus aureus infective endocarditis isolates.

doi:10.1016/j.diagmicrobio.2014.03.009

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Article

Superantigen profiling of Staphylococcus aureus infective endocarditis isolates.

Diagnostic microbiology and infectious disease - 1 Jun 2014

Chung Jin-Won, Karau Melissa J, Greenwood-Quaintance Kerryl E, Ballard Alessandro D, Tilahun Ashenafi, Khaleghi Shahryar Rostamkolaei, David Chella S, Patel Robin, Rajagopalan Govindarajan

Abstract excerpt

The frequency of superantigen production among Staphylococcus aureus isolates associated with endocarditis is not well defined. We tested 154 S. aureus isolates from definite infective endocarditis cases for the presence of staphylococcal enterotoxins A-E, H, and TSST-1 by PCR, enzyme-linked immunosorbent assay, and using an HLA-DR3 transgenic mouse splenocyte proliferation assay. Sixty-three isolates (50.8%)...

Topics

Adult
Aged
Aged, 80 and over
Animals
Cell Proliferation
Endocarditis
Enzyme-Linked Immunosorbent Assay
Female
Genotype
Humans
Leukocytes, Mononuclear

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Mice, Transgenic

Middle Aged

Polymerase Chain Reaction

Staphylococcal Infections

Staphylococcus aureus

Superantigens

Source

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Identifiers

PMID: 24745820
DOI: 10.1016/j.diagmicrobio.2014.03.009
PMCID: PMC4031024

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