Article
Impacts of enterotoxin gene cluster-encoded superantigens on local and systemic experimental Staphylococcus aureus infections.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology - 1 Jul 2015
Nowrouzian F L, Ali A, Badiou C, Dauwalder O, Lina G, Josefsson E
Abstract excerpt
Staphylococcus aureus is both a component of the normal skin flora and an important pathogen. It expresses a range of recognized and putative virulence factors, such as enterotoxins with superantigenic properties. Several superantigen genes, i.e., seg, sei, selm, seln, and selo, are encoded by the enterotoxin gene cluster (egc), which is found in the majority of S. aureus isolates. Carriage of egc is associated...
Topics
- Animals
- Disease Models, Animal
- Enterotoxins
- Female
- Gene Expression Regulation, Bacterial
- Genes, Bacterial
- Genetic Loci
- Humans
- Mice
- Multigene Family
