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Article

Inhibition enhancer of zeste homologue 2 promotes senescence and apoptosis induced by doxorubicin in p53 mutant gastric cancer cells.

Cell proliferation - 1 Jun 2014

Bai J, Ma M, Cai M, Xu F, Chen J, Wang G, Shuai X, Tao K

Abstract excerpt

OBJECTIVES: Enhancer of zeste homologue 2 (EZH2) is crucially involved in epigenetic silencing by acting as a histone methyltransferase. Although EZH2 is overexpressed in many cancers and is involved in malignant cell proliferation and invasion, the role of EZH2 in senescence induced by DNA damag...

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Identifiers

PMID: 24738879
DOI: 10.1111/cpr.12103
PMCID: PMC6495717

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Prepared record publication-24738879-2026-09-05.1. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 5 Sept 2026.

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