Article
Efficacy and safety of splenectomy in telaprevir-based triple therapy for chronic hepatitis C patients with thrombocytopenia and advanced fibrosis.
Journal of gastroenterology and hepatology - 1 Sept 2014
Ogawa Eiichi, Furusyo Norihiro, Nakamuta Makoto, Kajiwara Eiji, Nomura Hideyuki, Dohmen Kazufumi, Takahashi Kazuhiro, Satoh Takeaki, Azuma Koichi, Kawano Akira, Tanabe Yuichi, Kotoh Kazuhiro, Shimoda Shinji, Akahoshi Tomohiko, Maehara Yoshihiko, Hayashi Jun
Abstract excerpt
BACKGROUND AND AIM: Thrombocytopenia (TCP) of chronic hepatitis C patients with cirrhosis has a negative impact on the management of interferon-based treatment. The aim of this study is to evaluate the efficacy and safety of telaprevir-based triple therapy for patients who have undergone splenectomy (Spx). METHODS: This prospective, multicenter study consisted of 80 patients, including 32 Spx and 48 non-Spx/TCP...
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