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Article

Misinterpretation of TPMT by a DTC genetic testing company.

Clinical pharmacology and therapeutics - 1 Jun 2014

Brownstein C A, Margulies D M, Manzi S F

Abstract excerpt

23andme has suspended marketing of health-related reports due to US Food and Drug Administration approval violations. This has fostered discussions on the actual risks associated with consumer use of these reports. In the case described below, rare genotypes for the gene encoding thiopurine methyltransferase (TPMT) were misinterpreted by a direct-to-consumer (DTC) company, and risk calculations for breast cancer...

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Source

Identifiers

PMID: 24714787
DOI: 10.1038/clpt.2014.60

Genes

TPMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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