Article
A rare cause of susceptibility to neutropenic sepsis in a patient with metastatic pancreas cancer.
BMJ case reports - 3 Apr 2014
Suarez Martinez-Falero Beatriz, Gillmore Roopinder
Abstract excerpt
A 71-year-old patient receiving combination chemotherapy (irinotecan, oxaliplatin and 5-fluorouracil (5-FU)) for metastatic pancreas cancer was admitted after her first cycle of chemotherapy with a severe and unexpectedly prolonged episode of neutropenic sepsis associated with pancytopenia and marked mucositis. Owing to the unusual picture, the patient was tested for mutations in the gene encoding the enzyme...
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