Article
Human Papillomavirus Type 16 E6* Induces Oxidative Stress and DNA Damage
3 Apr 2014
Abstract excerpt
UNLABELLED: High-risk types of human papillomavirus (HPV) are the causative agents of virtually all cases of cervical cancer and a significant proportion of other anogenital cancers, as well as both oral and pharyngeal cancers. The high-risk types encode two viral oncogenes, E6 and E7, which work together to initiate cell transformation. Multiple steps involving the activities and interactions of both viral and...
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