Article
Discovering functions of unannotated genes from a transcriptome survey of wild fungal isolates.
mBio - 1 Apr 2014
Ellison Christopher E, Kowbel David, Glass N Louise, Taylor John W, Brem Rachel B
Abstract excerpt
Most fungal genomes are poorly annotated, and many fungal traits of industrial and biomedical relevance are not well suited to classical genetic screens. Assigning genes to phenotypes on a genomic scale thus remains an urgent need in the field. We developed an approach to infer gene function from expression profiles of wild fungal isolates, and we applied our strategy to the filamentous fungus Neurospora crassa....
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