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Article

Impact of folate therapy on combined immunodeficiency secondary to hereditary folate malabsorption.

Clinical immunology (Orlando, Fla.) - 1 Jul 2014

Kishimoto Kenji, Kobayashi Ryoji, Sano Hirozumi, Suzuki Daisuke, Maruoka Hayato, Yasuda Kazue, Chida Natsuko, Yamada Masafumi, Kobayashi Kunihiko

Abstract excerpt

Hereditary folate malabsorption (HFM) is a rare autosomal recessive disorder. Severe folate deficiency in HFM can result in immunodeficiency. We describe a female infant with HFM who acquired severe Pneumocystis pneumonia. The objective of the present study was to elucidate her immunological phenotype and to examine the time course of immune recovery following parenteral folate therapy. The patient demonstrated a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24691418
DOI: 10.1016/j.clim.2014.03.014

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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