Article
SWATH™- and iTRAQ-based quantitative proteomic analyses reveal an overexpression and biological relevance of CD109 in advanced NSCLC.
Journal of proteomics - 6 May 2014
Zhang Fanglin, Lin Hechun, Gu Aiqin, Li Jing, Liu Lei, Yu Tao, Cui Yongqi, Deng Wei, Yan Mingxia, Li Jinjun, Yao Ming
Abstract excerpt
To identify cancer-related proteins, we used isobaric tags in a relative and absolute quantitation (iTRAQ) proteomic approach and SWATH™ quantification approach to analyze the secretome of an isogenic pair of highly metastatic and low metastatic non-small-cell lung cancer (NSCLC) cell lines. In addition, we compared two groups of pooled serum samples (12 early-stage and 12 late-stage patients) to mine data for...
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