The phenotype of the good effort mutant zebrafish is retinal degeneration by cell death and is linked to the chromosome assembly factor 1b gene.

Abstract excerpt

In a screen to identify zebrafish eye mutants, we isolated the good effort (gef) mutant. The retina of gef embryos is characterized by the successful initiation of the optic primordium and normal retinal development over the first 2 days post fertilization (dpf). The mutant retina, however, fails to continue to grow. Embryos from gef heterozygous incrosses were analyzed for cell death by acridine orange and by...

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