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Moyamoya disease-associated protein mysterin/RNF213 is a novel AAA+ ATPase, which dynamically changes its oligomeric state.

Scientific reports - 24 Mar 2014

Morito Daisuke, Nishikawa Kouki, Hoseki Jun, Kitamura Akira, Kotani Yuri, Kiso Kazumi, Kinjo Masataka, Fujiyoshi Yoshinori, Nagata Kazuhiro

Abstract excerpt

Moyamoya disease is an idiopathic human cerebrovascular disorder that is characterized by progressive stenosis and abnormal collateral vessels. We recently identified mysterin/RNF213 as its first susceptibility gene, which encodes a 591-kDa protein containing enzymatically active P-loop ATPase an...

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PMID: 24658080
DOI: 10.1038/srep04442
PMCID: PMC3963067

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24658080-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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