Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A new strategy of promoting cisplatin chemotherapeutic efficiency by targeting endoplasmic reticulum stress

18 Oct 2013

Abstract excerpt

Cisplatin (cis‑diamminedichloroplatinum II, CDDP) is one of the most effective chemotherapeutic agents and is widely used in the treatment of solid tumors. However, its side effects and acquired resistance gained during the course of treatment may limit its usage. It is generally considered to be a cytotoxic drug that kills cancer cells by damaging their DNA and inhibiting DNA synthesis to induce apoptosis via...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy in Disease and Therapy
Share to DNA Repair Mechanisms
Share to Endoplasmic Reticulum Stress and Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24649299
DOI: 10.3892/mco.2013.202

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A new strategy of promoting cisplatin chemotherapeutic efficiency by targeting endoplasmic reticulum stressPMID 24649299Read ↗

Review. The endoplasmic reticulum: a target for new anticancer drugs.Semantic proximity Read ↗

Endoplasmic reticulum stress, cell death and tumor: Association between endoplasmic reticulum stress and the apoptosis pathway in tumors (Review)Semantic proximity Read ↗

Can Cisplatin Therapy Be Improved? Pathways That Can Be TargetedSemantic proximity Read ↗

Endoplasmic reticulum stress signaling and chemotherapy resistance in solid cancersSemantic proximity Read ↗

Cisplatin Is a DNA-Damaging Antitumour Compound Triggering Multifactorial Biochemical Responses in Cancer Cells: Importance of Apoptotic PathwaysSemantic proximity Read ↗

Systems biology of cisplatin resistance: past, present and futureSemantic proximity Read ↗

Protective Effect of Natural Antioxidants on Reducing Cisplatin-Induced NephrotoxicitySemantic proximity Read ↗

Elucidating Role of Reactive Oxygen Species (ROS) in Cisplatin Chemotherapy: A Focus on Molecular Pathways and Possible Therapeutic StrategiesSemantic proximity Read ↗

Targeting the hallmarks of cancer with therapy-induced endoplasmic reticulum (ER) stressSemantic proximity Read ↗

Endoplasmic Reticulum Stress and CancerSemantic proximity Read ↗

Molecular mechanisms of cisplatin resistance in ovarian cancerSemantic proximity Read ↗

Biomolecular Targets for Platinum Antitumor DrugsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.