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Article

Phosphoprotein analysis reveals MEK inhibition as a way to target non-small cell lung cancer tumor initiating cells.

International journal of radiation biology - 1 Aug 2014

Lundholm Lovisa, Hååg Petra, Juntti Therese, Lewensohn Rolf, Viktorsson Kristina

Abstract excerpt

PURPOSE: We aimed to analyze the activation status of commonly deregulated receptor tyrosine kinases (RTK) in human non-small cell lung cancer (NSCLC) tumor initiating cells (TIC) previously demonstrated to be refractory to ionizing radiation and chemotherapy. MATERIALS AND METHODS: Phosphorylated RTK and important signaling nodes were assayed using PathScan RTK Signaling Antibody Array Kit in NSCLC TIC and bulk...

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Identifiers

PMID: 24646078
DOI: 10.3109/09553002.2014.905725

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STAT1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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